As THC-O is about 3x as potent as delta-9, you can expect this cannabinoid to get you, well, pretty high. But, its psychoactive effects go beyond those associated with a typical THC high, such as feeling giggly, sleepy, and introspective. THC-O is nicknamed “the spiritual cannabinoid” for a reason. Unlike any other cannabinoid in cannabis, including both marijuana and hemp, THC-O-acetate produces a psychedelic experience, almost more similar to the intoxication associated with psilocybin.